Amfepramonum [INN-Latin]
Brand names,
Amfepramonum [INN-Latin]
Analogs
Amfepramonum [INN-Latin]
Brand Names Mixture
Amfepramonum [INN-Latin]
Chemical_Formula
C13H19NO
Amfepramonum [INN-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amfepramonum [INN-Latin]
fda sheet
Amfepramonum [INN-Latin]
msds (material safety sheet)
Amfepramonum [INN-Latin]
Synthesis Reference
No information avaliable
Amfepramonum [INN-Latin]
Molecular Weight
205.296 g/mol
Amfepramonum [INN-Latin]
Melting Point
No information avaliable
Amfepramonum [INN-Latin]
H2O Solubility
No information avaliable
Amfepramonum [INN-Latin]
State
No information avaliable
Amfepramonum [INN-Latin]
LogP
2.951
Amfepramonum [INN-Latin]
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amfepramonum [INN-Latin]
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amfepramonum [INN-Latin]
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amfepramonum [INN-Latin]
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amfepramonum [INN-Latin]
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amfepramonum [INN-Latin]
Patient Information
No information avaliable
Amfepramonum [INN-Latin]
Organisms Affected
Humans and other mammals